In April 2006 The New York Times reported that Interscope executives are working to produce their own television series based on the Pussycat Dolls and overseen by McG, the former video director who also directed the movie Charlie's Angels: Full Throttle.

In 2003, Nicole Scherzinger, a former member of the American Popstars winners Eden's Crush, became the group's lead singer. The present members of the group are Scherzinger,Carmit Bachar ; Jessica Sutta (who joined in 2002); and Melody Thornton, Kimberly Wyatt, and Ashley Roberts (who all joined in 2003). They opened the MTV Asia Awards 2004.

In 2005, The Pussycat Dolls released their debut album PCD. The album debuted at #5 on the Billboard 200, selling about 100,000 copies. It has produced four singles. "Don't Cha" (featuring Busta Rhymes) became their first major hit.

The follow-up, "Stickwitu", became the group's first U.S. # 1 Billboard Pop Radio hit,it went on to sell over a million digital downloads in the world and became their second #1 single in the UK. The third single, "Beep," featured Black Eyed Peas lead rapper will.i.am. They recently released their latest single, "Buttons," featuring Snoop Dogg which followed in the success of the previous singles and went straight into the top 5 on the UK singles chart, #3. The group's final single has been confirmed as the high tempo, club track Wait A Minute and is set for release next month, August 2006, in North America and I Don't Need A Man will be released in Europe.

The Pussycat Dolls are proving to be a recognised female group as MTV hits (UK) marks them as #1 in Top 10 Female Groups (July 2006) beating #2 Destiny's Child and #7 Spice Girls.

The group won a Billboard Music Award for "Don't Cha" as Top Hot/Dance Club Play Single of the Year. The song was also nominated for Top-Selling Single of the Year and Top-Selling Dance Single of the Year.

At the SXSW music conference in 2006, Interscope lawyer Darryl Franklin said, during a panel discussion, that the contract with the group is unique in that its members are actually salaried employees of the record label and, by design, completely interchangeable. This means that in addition to CD sales, the label also controls merchandise, web sites and all other commercial aspects of the group and their income, excluding song publishing.

Most recently, the Pussycat Dolls have ventured into the virtual world. In 2006, San Francisco-based company Doppelganger launched the PCD Music Lounge, an interactive website.

On June 30th's VSpot Top 20 Countdown, host Matt Pinfield announced that lead singer Nicole Scherzinger has written 12 new songs for the follow-up album to 2005's PCD.